RSS

Pigmented Spindle Cell Naevus of Reed: A Controversial Diagnostic Entity In Australia

24 Jun

Interesting article in the May 2011 edition of the Australasian Journal of Dermatology by Scott Webber, Greg Siller and Peter Soyer entitled ‘Pigmented Spindle Cell Naevus of Reed: A Controversial Diagnostic Entity In Australia.’

Points of note include

– Pigmented spindle cell naevus of Reed (PSCN) is a recognized distinctly separate entity away from Spitz naevus.

– The clinical and dermatoscopic features of Spitz naevi and melanoma overlap with PSCN.

– Clinical diagnosing of PSCN by dermatology training groups remains difficult.

– Well defined dermatoscopic and physical criteria for lesional morphology and histopathological characteristics are available and have increased the accuracy in distinguishing PSCN from Spitz naevi and melanoma.

– An accurate diagnosis is best gained from clinicopathological correlation.

– PSCN typically occurs in young women, only 25% of cases in patients > 30 years old.

– Punch biopsy as initial management is not recommended as misdiagnosis as melanoma is more likely.

I recommend reading the entire article. Below is a link.

http://onlinelibrary.wiley.com/doi/10.1111/j.1440-0960.2011.00743.x/abstract

Thanks for reading and I welcome any comments

Follow me on twitter (@skinpathology)

Keep an eye out for my website coming soon (www.skinpathonline.com)

Feel free to email me with any questions or queries on feedback@skinpathonline.com

Advertisements
 

Tags: , , , , , , , , , , , , , , , , , , , , , , , , , , , ,

2 responses to “Pigmented Spindle Cell Naevus of Reed: A Controversial Diagnostic Entity In Australia

  1. Mitchell Wan

    June 24, 2011 at 12:28 pm

    Hi,
    Would FXIIIa be useful for Spindle cell identification – indicating it is more than likely a PSCN vs MM?

     
    • skinpathonline

      June 25, 2011 at 12:50 am

      Not really FXIIIa. As PSCN and MM are both melanocytic tumours FXIIia would not have any diagnostic advantage. Thanks for you comment.

       

Leave a Reply

Fill in your details below or click an icon to log in:

WordPress.com Logo

You are commenting using your WordPress.com account. Log Out / Change )

Twitter picture

You are commenting using your Twitter account. Log Out / Change )

Facebook photo

You are commenting using your Facebook account. Log Out / Change )

Google+ photo

You are commenting using your Google+ account. Log Out / Change )

Connecting to %s

 
%d bloggers like this: