Melanoma – Prognostic Factors – Quick Overview

16 Mar

Hi again

I received many questions regarding melanoma and its prognostic factors so I summarised most of the important ones below and have given a brief, general description for each.

AGE – the older the patient, the poorer the prognosis.

SEX – generally females have a better prognosis than males.

BODY SITE – melanomas on the extremities (eg. legs and arms) have a better prognosis than those on the neck, trunk and face.

INVOLVEMENT OF LYMPH NODES – presence of tumour lymph node involvement has a poorer prognosis. Generally the more nodes involved the poorer the prognosis.

TUMOUR THICKNESS – the thicker the melanoma the poorer the prognosis.

ULCERATION – the presence of ulceration indicates a poorer prognosis.

MITOTIC RATE – the higher the mitotic rate the poorer the prognosis.

REGRESSION – presence of regression in thin melanomas indicates a poorer prognosis.

There are a few other prognostic factors such as Clarks level, tumour-infiltrating lymphocytes, BRAF mutations and LDH (lactate dehydrogenase) serum level.

Many thanks for reading and please leave any comments you wish.

Keep an eye out for my website coming soon

Follow me on twitter as well (@skinpathology)


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2 responses to “Melanoma – Prognostic Factors – Quick Overview

  1. The Jump Rope Queen

    June 16, 2011 at 2:09 am

    Hello! Thank you for your comment on my blog earlier. I had to erase that one and start over and it erased your comment, but I APPRECIATE your feedback and feel free to comment again 🙂 I am glad to know of someone else who is passionate about helping raise awareness to skin cancer! Best of luck to you! ~Jamie Len

  2. joe

    July 29, 2011 at 9:02 pm

    thank you wish i could have had this info about 2 years ago


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